Open AccessA novel reverse phase high-performance liquid chromatography method for standardization of Orthosiphon stamineus leaf extracts
Author(s) -
Noor Hafizoh Saidan,
Abdalrahim F. A. Aisha,
Mohd Shahrul Ridzuan Hamil,
Amin Malik Shah Abdul Majid,
Zhari Ismail
Publication year - 2015
Publication title -
pharmacognosy research
Language(s) - English
Resource type - Journals
eISSN - 0976-4836
pISSN - 0974-8490
DOI - 10.4103/0974-8490.147195
Subject(s) - chromatography , formic acid , rosmarinic acid , chemistry , high performance liquid chromatography , organic chemistry , antioxidant
Orthosiphon stamineus Benth. (Lamiaceae) is a traditional medicinal plant which has been used in treating various ailments such as kidney diseases, bladder inflammation, arthritis and diabetes. The leaves contain high concentration of phenolic compounds, thus, rosmarinic acid (RA), 3'-hydroxy-5, 6, 7, 4'-tetramethoxyflavone (TMF), sinensetin (SIN) and eupatorin (EUP) were chosen as a marker compounds for standardization of various O. stamineus leaf extracts.