Open AccessAntioxidant and toxicological evaluation ofCassia sopherain streptozotocin-induced diabetic Wistar rats
Author(s) -
Rambir Singh,
Priyanka Bhardwaj,
Poonam Sharma
Publication year - 2013
Publication title -
pharmacognosy research
Language(s) - English
Resource type - Journals
eISSN - 0976-4836
pISSN - 0974-8490
DOI - 10.4103/0974-8490.118767
Subject(s) - oxidative stress , streptozotocin , glutathione peroxidase , antioxidant , pharmacology , diabetes mellitus , aspartate transaminase , lipid peroxidation , superoxide dismutase , chemistry , glutathione , endocrinology , medicine , alkaline phosphatase , biochemistry , enzyme
Multiple-organ failure is the main cause of death in diabetes mellitus (DM). Hyperglycemia-induced oxidative stress is responsible for major diabetic complications, including multiple-organ failure. Medicinal plants possessing antioxidant activity may reduce oxidative stress and improve the functions of various organs affected by hyperglycemia.