Open AccessProstatic intraepithelial neoplasia-like ductal prostatic adenocarcinoma: A case suitable for active surveillance?
Author(s) -
Soroush RaisBahrami,
Melissa R Dillard,
Guochun Zhu,
Jennifer Gordetsky
Publication year - 2017
Publication title -
urology annals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.355
H-Index - 20
eISSN - 0974-7834
pISSN - 0974-7796
DOI - 10.4103/0974-7796.198829
Subject(s) - medicine , high grade prostatic intraepithelial neoplasia , prostate cancer , intraepithelial neoplasia , prostate , adenocarcinoma , magnetic resonance imaging , urology , prostatic adenocarcinoma , cancer , pathology , radiology
In contrast to typical prostatic ductal adenocarcinoma, prostatic intraepithelial neoplasia (PIN)-like ductal adenocarcinoma is a rare variant of prostate cancer with low-grade clinical behavior. We report a case of a 66-year-old African-American male with an elevated serum prostate-specific antigen who underwent multiparametric prostate magnetic resonance imaging (MRI) and MRI/ultrasound fusion-guided biopsies. Pathology demonstrated low-volume Gleason score 3 + 3 = 6 (Grade Group 1), acinar adenocarcinoma involving one core and PIN-like ductal adenocarcinoma on a separate core. Herein, we discuss the potential role of active surveillance for patients with this rare variant of prostate cancer found in the era of advanced imaging with multiparametric MRI for prostate cancer.