Open AccessCisplatin and bleomycin-induced acute peripheral-vascular stenosis in patient with testicular cancer
Author(s) -
Tayyar Alp Özkan,
Ufuk Aydın,
Derih Ay,
İrfan Cebeci
Publication year - 2016
Publication title -
urology annals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.355
H-Index - 20
eISSN - 0974-7834
pISSN - 0974-7796
DOI - 10.4103/0974-7796.192096
Subject(s) - medicine , bleomycin , testicular cancer , cisplatin , etoposide , chemotherapy , peripheral , cardiology , occlusion , surgery , oncology
After cisplatin and bleomycin-containing chemotherapy (CTx) for testicular cancer, part of the patients may develop acute or long-term cardiovascular toxicity. In the present case, we reported that a 58-year-old male patient presenting with testicular tumors who developed acute peripheral arterial disease during combination CTx with bleomycin, etoposide, and cisplatin. Superficial femoral artery occlusion not responded to structure thrombolytic and anticoagulators treatment. Left lower extremity was amputated below knee. In patients with high risk of cardiovascular disease, prophylactic anticoagulation may be recommended. The risk of causing factors of thromboembolism in patients with testicular cancer under cisplatin and bleomycin-containing CTx should be evaluated.