Open AccessRole of Vitamin C and E supplementation in reduction of serum level of renal injury marker following shock wave lithotripsy: Prospective single centre experience
Author(s) -
Jayesh Modi,
Pranjal Modi,
Bipin Chandra Pal,
Jyoti Bansal,
Suresh Kumar,
Ramya Nagarajan,
Yusuf Saifee
Publication year - 2015
Publication title -
urology annals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.355
H-Index - 20
eISSN - 0974-7834
pISSN - 0974-7796
DOI - 10.4103/0974-7796.156143
Subject(s) - medicine , lithotripsy , vitamin d and neurology , urology , oxidative stress , gastroenterology , prospective cohort study , surgery
Shock wave lithotripsy has become first line treatment modality for renal calculi due to its noninvasiveness. However, the destructive forces like dispersion of cavitation bubbles can cause trauma to thin-walled vessels and renal parenchyma during fragmentation of the stones. Antioxidants are our first line of defense against oxidative stress. The aim of this study was to investigate whether oral administration of Vitamin C and E help in a reduction of the serum level of inflammatory mediator by serial measurement of high sensitivity C-reactive protein (hs-CRP) and by this reduction in the risk of renal damage.