Open AccessSimultaneous renal clear cell carcinoma and gastrointestinal stromal tumor in one case
Author(s) -
Ji Wen,
Hanzhong Li,
Zhi Gang Ji,
Wei Gang-Yan,
Bing Shi
Publication year - 2013
Publication title -
urology annals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.355
H-Index - 20
eISSN - 0974-7834
pISSN - 0974-7796
DOI - 10.4103/0974-7796.110013
Subject(s) - sunitinib , renal cell carcinoma , medicine , stromal cell , stromal tumor , gist , tyrosine kinase inhibitor , kidney , tyrosine kinase , cancer research , stomach , receptor tyrosine kinase , sunitinib malate , pathology , small intestine , oncology , cancer , receptor
Renal cell carcinoma is a tumor in kidney, while gastrointestinal stromal tumors are localized in the stomach and small intestine. They seldom occur simultaneously in sporadic case, both of which were suspective to sunitinib, a tyrosine kinases (RTKs) inhibitor. Our current case is novel in that concurrent RTK-related tumors are involved in one case. One possible explanation is the presence of some activating mutations.