Open AccessPrevalence of Mupirocin Resistance Among Staphylococci, its Clinical Significance and Relationship to Clinical Use
Author(s) -
Manohar Shoorashetty Rudresh,
Giriyapur Siddappa Ravi,
Aravind Motagi,
Ann Mary Alex,
Parthasarathi Sandhya,
Bangalore Viswanath Navaneeth
Publication year - 2015
Publication title -
journal of laboratory physicians
Language(s) - English
Resource type - Journals
eISSN - 0974-7826
pISSN - 0974-2727
DOI - 10.4103/0974-2727.163127
Subject(s) - mupirocin , staphylococcus aureus , microbiology and biotechnology , medicine , staphylococcus epidermidis , drug resistance , antibiotics , methicillin resistant staphylococcus aureus , staphylococcus , staphylococcal infections , staphylococcus haemolyticus , biology , bacteria , genetics
Mupirocin competitively inhibits bacterial isoleucyl transfer-RNA synthetase and inhibit bacterial protein synthesis. Widespread usage and over the counter availability of the drug has resulted in resistance among Staphylococcus species.