Open Access
Principles and methods of preparation of platelet-rich plasma: A review and author′s perspective
Author(s) -
Rachita Dhurat,
Mathapati Shivamurthy Sukesh
Publication year - 2014
Publication title -
journal of cutaneous and aesthetic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.44
H-Index - 13
eISSN - 0974-5157
pISSN - 0974-2077
DOI - 10.4103/0974-2077.150734
Subject(s) - platelet rich plasma , medicine , confusion , terminology , perspective (graphical) , standardization , protocol (science) , platelet , intensive care medicine , surgery , pathology , immunology , alternative medicine , computer science , artificial intelligence , psychology , linguistics , philosophy , psychoanalysis , operating system
The utility of platelet-rich plasma (PRP) has spanned various fields of dermatology from chronic ulcer management to trichology and aesthetics, due to its role in wound healing. Though PRP is being used over a long time, there is still confusion over proper terminology to define, classify and describe the different variations of platelet concentrates. There is also a wide variation in the reported protocols for standardization and preparation of PRP, in addition to lack of accurate characterization of the tested products in most articles on the topic. Additionally, the high cost of commercially available PRP kits, precludes its use over a larger population. In this article, we review the principles and preparation methods of PRP based on available literature and place our perspective in standardizing a safe, simple protocol that can be followed to obtain an optimal consistent platelet yield.