Open AccessTamoxifen: An alternative to clomiphene in women with polycystic ovary syndrome
Author(s) -
Lakhbir Kaur Dhaliwal,
Vanita Suri,
Kewal Krishan Gupta,
Sumitu Sahdev
Publication year - 2011
Publication title -
journal of human reproductive sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.484
H-Index - 31
eISSN - 0974-1208
pISSN - 1998-4766
DOI - 10.4103/0974-1208.86085
Subject(s) - anovulation , polycystic ovary , pregnancy , medicine , infertility , pregnancy rate , ovulation , gynecology , tamoxifen , obstetrics , ovulation induction , menstrual cycle , fertility , population , cancer , hormone , insulin , biology , breast cancer , insulin resistance , genetics , environmental health
Clomiphene citrate is commonly used for ovulation induction in women with anovulatory infertility. However, pregnancy rates with this drug are not as good as ovulation rates. Tamoxifen may be a better choice in some patients who fail to either ovulate or conceive with clomiphene due to its favorable effect on the cervical mucus and endometrium. This study was conducted to evaluate the role of tamoxifen in women with anovulatory infertility and find out the optimum dose needed for achieving the best outcome.