Open AccessSuccessful live birth after rescue ICSI following failed fertilization
Author(s) -
Neeta Singh,
Neena Malhotra,
Unnati Shende,
Abanish Tiwari
Publication year - 2013
Publication title -
journal of human reproductive sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.484
H-Index - 31
eISSN - 0974-1208
pISSN - 1998-4766
DOI - 10.4103/0974-1208.112388
Subject(s) - intracytoplasmic sperm injection , human fertilization , live birth , oocyte activation , medicine , andrology , in vitro fertilisation , oocyte , obstetrics , gynecology , biology , pregnancy , embryo , anatomy , genetics
In a conventional IVF cycle unexpected complete fertilization failure may occur in 10-25% of infertile women. To overcome this barrier of fertilization failure, some investigators have suggested intracytoplasmic sperm injection (ICSI) on day 1 of an unfertilized mature oocyte, the so called "rescue ICSI". We report a case of fertilization failure followed by rescue ICSI resulting in a live birth. Although the success of rescue ICSI is still questionable, this procedure is worth an attempt in order to give the best chance to the couple in that cycle.