
Red cell alloimmunization in repeatedly transfused patients
Author(s) -
Dimel K Bhuva,
Jitendra H Vachhani
Publication year - 2017
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/0973-6247.214347
Subject(s) - medicine , antibody , thalassemia , red blood cell , red cell , splenectomy , antigen , blood transfusion , immunology , globulin , spleen
Repeated blood transfusions can result in the production of alloantibodies against one or more red cell antigens, which complicates subsequent transfusions. Aims: The study was done to find incidence of various red cell alloantibodies; to determine the type of alloantibody; to identify the factors such as frequency of transfusion, splenectomy status, donor ethnicity and gender and their association with the development of antibody in repeatedly transfused patients.