Open AccessAutologous peripheral blood stem cell harvest: Collection efficiency and factors affecting it
Author(s) -
Aseem Kumar Tiwari,
Prashant Pandey,
Harini Subbaraman,
Rahul Bhargava,
Ganesh Rawat,
Shivani Madiraju,
Vimarsh Raina,
Richa Bhargava
Publication year - 2016
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/0973-6247.164273
Subject(s) - leukapheresis , medicine , cd34 , hematocrit , apheresis , surgery , stem cell , platelet , biology , genetics
Harvest of hematopoietic progenitor cells via leukapheresis is being used increasingly for transplants in India. Adequate yield of cells per kilogram body weight of recipient is required for successful engraftment. Collection efficiency (CE) is an objective quality parameter used to assess the quality of leukapheresis program. In this study, we calculated the CE of the ComTec cell separator (Fresenius Kabi, Germany) using two different formulae (CE1 and CE2) and analyzed various patient and procedural factors, which may affect it.