Open AccessAnti-G antibody in alloimmunized pregnant women: Report of two cases
Author(s) -
Raj Nath Makroo,
Anita Kaul,
Aakanksha Bhatia,
Soma Agrawal,
Chanchal Singh,
Prashant Karna
Publication year - 2015
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/0973-6247.162724
Subject(s) - medicine , antibody , fetus , pregnancy , isoantibodies , obstetrics , disease , hemolytic disease of the newborn (abo) , haemolytic disease , immunology , pathology , genetics , biology
Anti-G has been reported as a possible cause of hemolytic disease of the fetus and newborn (HDFN), either independently or in association with anti-D, anti-C or both. The antibody mimics the pattern of anti-C and anti-D reactivity in the identification panel and is often present along with either or both of these antibodies. The differentiation of anti-D, -C and-G in routine pretransfusion workup is particularly essential in antenatal cases. We report two antenatal cases where anti-G was identified on advanced immunohematological workup, in addition to other alloantibodies.