Open AccessClinical and serological characterization of cold agglutinin syndrome in a Tertiary Care Hospital in Eastern India
Author(s) -
Sudipta Sekhar Das,
Soumya Bhattacharya,
Shilpa Bhartia
Publication year - 2015
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/0973-6247.154258
Subject(s) - medicine , cold agglutinin , serology , exacerbation , cold agglutinin disease , anemia , autoimmune hemolytic anemia , pallor , hemolytic anemia , hemolysis , pediatrics , immunology , antibody
Cold agglutinin syndrome (CAS) primary or secondary represents approximately 16-32% of autoimmune hemolytic anemia cases. Most patients present with mild, chronic hemolytic anemia with exacerbation of the condition in the cold environment. Red cell transfusions are only indicated when there is a life-threatening anemia causing crisis. We studied the clinical and serological characterization of CAS with the aim that the information gained from this study would help in proper diagnosis and management of these patients.