Open AccessEvaluation of a new serological test for syphilis based on chemiluminescence assay in a tertiary care hospital
Author(s) -
Aseem Kumar Tiwari,
Prashant Pandey,
Ravi C Dara,
Ganesh Rawat,
Vimarsh Raina,
Richa Bhargava
Publication year - 2015
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/0973-6247.150955
Subject(s) - syphilis , medicine , serology , virology , hbsag , immunology , chemiluminescence , antibody , hepatitis b virus , virus , human immunodeficiency virus (hiv) , chemistry , organic chemistry
Syphilis is a transfusion transmissible infections and it is mandatory to do serological test for syphilis (STS) on all donor blood samples. STS is usually based on detection of antibodies against the cardiolipin-lecithin antigen or against the Treponema-specific antigen. STS with good sensitivity and specificity helps enhance blood safety and consolidation of STS along with other transfusion transmittable infections such as human immunodeficiency virus, hepatitis-C virus, and hepatitis-B virus helps in reducing the errors and enhances efficiency.