Open AccessIgE- and IgG mediated severe anaphylactic platelet transfusion reaction in a known case of cerebral malaria
Author(s) -
Shanthi Bonagiri,
Bhavanadhar,
Priscilla Chandran,
A. Krishna Prasad
Publication year - 2013
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/0973-6247.106748
Subject(s) - medicine , immunoglobulin e , immunology , anaphylaxis , desensitization (medicine) , anaphylactic reaction , antibody , hypersensitivity reaction , allergy , anaphylactic reactions , exchange transfusion , platelet transfusion , platelet , receptor
Allergic reactions occur commonly in transfusion practice. However, severe anaphylactic reactions are rare; anti-IgA (IgA: Immunoglobulin A) in IgA-deficient patients is one of the well-illustrated and reported causes for such reactions. However, IgE-mediated hypersensitivity reaction through blood component transfusion may be caused in parasitic hyperimmunization for IgG and IgE antibodies.