Open AccessAssessment of In vitro antibacterial activity and cytotoxicity effect of Nigella sativa oil
Author(s) -
Ayşe Rüveyda Uğur,
Hatice Türk Dağı,
Bahadır Öztürk,
Gülsüm Tekin,
Duygu Fındık
Publication year - 2016
Publication title -
pharmacognosy magazine
Language(s) - English
Resource type - Journals
eISSN - 0976-4062
pISSN - 0973-1296
DOI - 10.4103/0973-1296.191459
Subject(s) - nigella sativa , staphylococcus aureus , microbiology and biotechnology , broth microdilution , methicillin resistant staphylococcus aureus , cytotoxicity , antibacterial activity , minimum inhibitory concentration , antibiotics , biology , in vitro , medicine , traditional medicine , bacteria , biochemistry , genetics
Methicillin resistance is a serious health concern since it has spread among Staphylococcus aureus and coagulase-negative Staphylococci (CoNS) that are frequent community and nosocomial pathogens worldwide. Methicillin-resistant strains are often resistant to other classes of antibiotics, making their treatment difficult. Nigella sativa oil is known to be active against Gram-positive cocci, yet its in vitro cytotoxicity is rarely investigated, is a proper and powerful candidate for treatment of methicillin-resistant isolates.