Open AccessThe antioxidant potential of Azadirachta indica ameliorates cardioprotection following diabetic mellitus-induced microangiopathy
Author(s) -
Naveen Gupta,
Nidhi Srivastva,
Parvesh Bubber,
Sanjeev Puri
Publication year - 2016
Publication title -
pharmacognosy magazine
Language(s) - English
Resource type - Journals
eISSN - 0976-4062
pISSN - 0973-1296
DOI - 10.4103/0973-1296.185772
Subject(s) - diabetes mellitus , streptozotocin , antioxidant , medicine , endocrinology , lipid peroxidation , cardioprotection , intraperitoneal injection , glutathione , oxidative stress , chemistry , pharmacology , biochemistry , enzyme , ischemia
Cardiac complications associated with diabetes mellitus have become major cause of concern. Antidiabetic drugs, with varied mode of action, are although available, apprehensions exist for their limited action or side effects upon prolonged use. Efforts are therefore inclined toward finding other alternatives. The present study was, thus, undertaken to evaluate the cardioprotective effect of Azadirachta indica (AI) on microangiopathic changes in rat model of diabetes.