Open AccessAn efficient high-performance liquid chromatography combined with electrospray ionization tandem mass spectrometry method to elaborate the changes of components between the raw and processed radix Aconitum kusnezoffii
Author(s) -
Beibei Wang,
Jiaojiao Ji,
Shuang Zhao,
Jing Dong,
Peng Tan,
Shengsang Na,
Yonggang Liu
Publication year - 2016
Publication title -
pharmacognosy magazine
Language(s) - English
Resource type - Journals
eISSN - 0976-4062
pISSN - 0973-1296
DOI - 10.4103/0973-1296.175989
Subject(s) - decoction , electrospray ionization , traditional medicine , radix (gastropod) , aconitum , mass spectrometry , chromatography , chemistry , tandem mass spectrometry , high performance liquid chromatography , traditional chinese medicine , aconitine , alkaloid , medicine , stereochemistry , botany , biology , alternative medicine , pathology
Crude radix Aconitum kusnezoffii (RAK) has great toxicity. Traditional Chinese medicine practice proved that processing may decrease its toxicity. In our previous study, we had established a new method of RAK processing (Paozhi). However, the mechanism is yet not perfect.