Open AccessIsolation and identification of cytotoxic compounds from the rhizomes of Paris quadrifolia L.
Author(s) -
Jerzy Gajdus,
Zbigniew Kaczyński,
Anna Kawiak,
Ewa Łojkowska,
Justyna Stefanowicz–Hajduk,
J. Renata Ochocka,
Piotr Stepnowski
Publication year - 2014
Publication title -
pharmacognosy magazine
Language(s) - English
Resource type - Journals
eISSN - 0976-4062
pISSN - 0973-1296
DOI - 10.4103/0973-1296.133289
Subject(s) - rhizome , hela , chemistry , saponin , glycoside , column chromatography , traditional medicine , cytotoxic t cell , cytotoxicity , stereochemistry , in vitro , chromatography , biochemistry , medicine , alternative medicine , pathology
Paris quadrifolia L. is a medicinal plant which contains steroidal saponins. The present study reports isolation and structural identification of six pennogenyl saponins obtained from P. quadrifolia rhizomes. The four spirostan saponins were obtained from P. quadrifolia for the first time. The cytotoxic effects of the sub-fractions and six compounds isolated from the plant extract were evaluated on tumour cells.