Open AccessLinum narbonense: A new valuable tool for biotechnological production of a potent anticancer lignan Justicidine B
Author(s) -
Илиана Йонкова,
Pavlina Sasheva,
Todor Ionkov,
Georgi Momekov
Publication year - 2013
Publication title -
pharmacognosy magazine
Language(s) - English
Resource type - Journals
eISSN - 0976-4062
pISSN - 0973-1296
DOI - 10.4103/0973-1296.108138
Subject(s) - lignan , bioreactor , linum , callus , agrobacterium , biomass (ecology) , botany , chemistry , microbiology and biotechnology , biology , food science , transformation (genetics) , biochemistry , agronomy , gene
Arylnaphthalene lignan Justicidin B is a lead compound in the management of bone cancer and osteoclastogenesis. The compound is the main cytotoxic principle of rare medicinal plant Linum narbonense L. (Linaceae). However, there have been no reports on the bioreactor production of justicidin B.