Open AccessGabapentin for chronic refractory cancer cough
Author(s) -
Shrikant Atreya,
Gaurav Kumar,
Soumitra Shankar Datta
Publication year - 2016
Publication title -
indian journal of palliative care/indian journal of palliative care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 26
eISSN - 1998-3735
pISSN - 0973-1075
DOI - 10.4103/0973-1075.173940
Subject(s) - medicine , gabapentin , chronic cough , refractory (planetary science) , anesthesia , pathophysiology , lung cancer , dermatology , pathology , asthma , physics , alternative medicine , astrobiology
Vagal sensory neuropathy or vagal hypersensitivity has been implicated in the pathophysiology of chronic cough. Earlier reports have shown gabapentin to be effective in sensory laryngeal neuropathy and symptom conditions that have a proven neural origin. We present a case report of a patient with chronic refractory cough due to a soft tissue mass in the lung that caused compression of the mediastinal structures. The patient was successfully treated with gabapentin with reduction in the cough intensity, duration, and frequency.