Open AccessPalliative radiotherapy in locally advanced head and neck cancer after failure of induction chemotherapy: Comparison of two fractionation schemes
Author(s) -
Kailash Chandra Pandey,
Swaroop Revannasiddaiah,
Nirdosh Kumar Pant,
Vipul Nautiyal,
Madhup Rastogi,
Manoj Kumar Gupta
Publication year - 2013
Publication title -
indian journal of palliative care/indian journal of palliative care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 26
eISSN - 1998-3735
pISSN - 0973-1075
DOI - 10.4103/0973-1075.121522
Subject(s) - medicine , quality of life (healthcare) , hazard ratio , induction chemotherapy , head and neck cancer , oncology , performance status , chemotherapy , taxane , radiation therapy , head and neck squamous cell carcinoma , log rank test , cancer , confidence interval , surgery , survival analysis , breast cancer , nursing
Among patients with locally advanced head and neck squamous cell cancers (LAHNSCC), the prognosis after nonresponse or progression despite induction chemotherapy (IC) is dismal, and further treatment is often palliative in intent. Given that nonresponse to chemotherapy could indicate subsequent radioresistance, we intended to assess the outcomes with two different fractionation schemes.