Open AccessEvaluation of myofibroblasts in oral squamous cell carcinoma using H1 calponin: An immunohistochemical study
Author(s) -
Kesavan Ganesan,
R Madhavan Nirmal,
Marwa Nassar,
Veeran Veeravarmal,
R Amsaveni,
Arul Kumar
Publication year - 2015
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/0973-029x.157200
Subject(s) - pathology , calponin , myofibroblast , epithelium , stroma , stromal cell , immunohistochemistry , oral mucosa , immunostaining , biology , medicine , fibrosis
Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral mucosa. Stromal myofibroblasts play an important role in tumor invasion and metastasis, due to its ability to modify the extracellular matrix. The purpose of this study was to evaluate and compare the presence of myofibroblasts in normal mucosa, early invasive carcinoma and different grades of OSCC.