Open AccessTriology of nitric oxide, mast cell and stress in pathogenesis of oral lichen planus
Author(s) -
Charu Kapoor,
Vijay Wadhwan,
Sharad Vaidya,
Sangeeta Malik
Publication year - 2013
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/0973-029x.119741
Subject(s) - oral lichen planus , pathogenesis , mast cell , griess test , saliva , nitric oxide , immunology , medicine , gastroenterology , chemistry , nitrite , organic chemistry , nitrate
Oral Lichen planus (OLP) is chronic, autoimmune, mucocutaneous disease. Numerous etiological factors have been proposed, but an authoritative and exact source of the disease has not been brought forward. Reactive nitrogen species (RNS), mast cell (MC) and stress are considered to play a key role in inflammation-mediated carcinogenesis generating nitric oxide (NO).