Open AccessBronchoalveolar lavage fluid cytokine bead array profile for prognostication of ventilated trauma patients
Author(s) -
Subodh Kumar,
Nidhi Bhardwaj,
Surbhi Khurana,
Amit Gupta,
Kapil Dev Soni,
Richa Aggrawal,
Purva Mathur
Publication year - 2016
Publication title -
indian journal of critical care medicine/indian journal of critical care medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 30
eISSN - 1998-359X
pISSN - 0972-5229
DOI - 10.4103/0972-5229.190375
Subject(s) - medicine , bronchoalveolar lavage , proinflammatory cytokine , ventilator associated pneumonia , cytokine , pneumonia , tumor necrosis factor alpha , immunology , gastroenterology , intensive care , inflammation , lung , intensive care medicine
Ventilator-associated pneumonia (VAP) is a common cause of mortality in trauma patients admitted to Intensive Care Units. The outcome of such patients may be dependent on local host immune response, which may be best reflected in studies using bronchoalveolar lavage (BAL) fluid. The present study was conducted to ascertain the cytokine profile of BAL using the cytometric bead array (CBA) in a flow cytometer and to correlate the levels of Th-1/Th-2 cytokines in BAL with the clinical outcome of ventilated trauma patients.