Open AccessCerebral toxoplasmosis masquerading CNS lymphoma on FDG PET-CT in post renal transplant patient
Author(s) -
Anirban Mukherjee,
Chandrasekhar Bal,
Madhavi Tripathi,
Chandan Jyoti Das,
Shamim Ahmed Shamim
Publication year - 2017
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/0972-3919.202254
Subject(s) - medicine , lesion , brain biopsy , toxoplasmosis , cerebellar hemisphere , renal transplant , stereotactic biopsy , biopsy , pathology , lymphoma , radiology , magnetic resonance imaging , transplantation , surgery
20 year old post renal transplant patient developed recurrent episodes of seizure. MRI revealed focal lesion in right parieto-occipital lobe with perilesional edema. FDG PET-CT revealed multiple hypermetabolic lesions in bilateral cerebral hemisphere. Subsequent biopsy from the lesion demonstrated bradyzoites of Toxoplasma gondii with inflammatory cells and thereby, a confirmatory diagnosis of cerebral toxoplasmosis was made. This case demonstrates the fact that increased FDG uptake in cerebral lesions in post transplant patient should be interpreted with caution and confirmed with histopathological correlation.