Open AccessPSMA expression in multinodular thyroid neoplasm on simultaneous Ga-68-PSMA PET/MRI
Author(s) -
Amarnath Jena,
Shuaib Zaidi,
Vikas Kashyap,
Karel Pacák,
Sangeeta Taneja
Publication year - 2017
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/0972-3919.202248
Subject(s) - medicine , thyroid , immunohistochemistry , pathology , prostate , thyroid carcinoma , thyroglobulin , neoplasm , radiology , cancer
PSMA PET is increasingly being used in imaging of recurrent prostate carcinoma. A case with suspected recurrent Prostate carcinoma (PCa), raised PSA (Prostate specific antigen) and suspected spinal metastases was referred for whole body Ga-68-PSMA PET/MRI. The study revealed PSMA avid recurrent prostate mass and extensive osseous metastases. Abnormal PSMA uptake in the thyroid gland prompted USG-guided FNAC which revealed Hurthle cell neoplasm. Histopathological examination (HPE) of excised gland showed multiple Hurthle cell adenomas in both lobes of thyroid along with foci of papillary thyroid carcinoma which on immunohistochemistry were thyroglobulin positive and PSA negative.