Open AccessPreparation and preclinical evaluation of68Ga-DOTA-amlodipine for L-type calcium channel imaging
Author(s) -
Tahereh Firuzyar,
Amir Reza Jalilian,
Mohammad Reza Aboudzadeh,
Hossein Sadeghpour,
Mahdi Shafiee-Ardestani,
Ali Khalaj
Publication year - 2016
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/0972-3919.190797
Subject(s) - biodistribution , amlodipine , dota , medicine , nuclear medicine , calcium , calcium channel , radiochemistry , chelation , in vitro , chemistry , biochemistry , organic chemistry , blood pressure
In order to develop a possible tracer for L-type calcium channel imaging, we here report the development of a Ga-68 amlodipine derivative for possible PET imaging.