Open AccessFlip-flop phenomenon in systemic sclerosis on fluorodeoxyglucose positron emission tomography/computed tomography
Author(s) -
Kevser Öksüzoğlu,
Gülşen Özen,
Sabahat İnanır,
Haner Direskeneli
Publication year - 2015
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/0972-3919.164018
Subject(s) - medicine , positron emission tomography , positron emission tomography computed tomography , fluorodeoxyglucose , computed tomography , connective tissue disease , nuclear medicine , tomography , radiology , pathology , autoimmune disease , disease
Systemic sclerosis (SSc) is a rare autoimmune disease, which may affect multiple organ systems. Fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) can demonstrate the degree and anatomical extent of involvement in the entire body and coexisting malignancies in connective tissue diseases. We present a case of SSc with an increased 18F-FDG uptake in the cutaneous and subcutaneous tissues even higher than the neighboring skeletal muscles ("flip-flop phenomenon," that is, an increased 18F-FDG uptake in the skin but a decreased 18F-FDG uptake in the skeletal muscles).