Open AccessSolid variant of papillary carcinoma thyroid in a child with no history of radiation exposure
Author(s) -
Nishikant Damle,
S. Ramya,
Chandrasekhar Bal,
Prashant Durgapal
Publication year - 2011
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/0972-3919.106707
Subject(s) - medicine , thyroid carcinoma , histopathology , thyroid , malignancy , pathology , differential diagnosis , metastasis , papillary carcinoma , radiation exposure , medullary cavity , medullary carcinoma , cancer , nuclear medicine
Solid variant is a rare and poorly characterized variant of papillary thyroid carcinoma (PTC) and comprises approximately 3% of PTCs. It is more common in children and has high propensity for extrathyroidal metastasis. It is seen in higher proportion in post-radiation PTCs and has been seen in more than one-third of post Chernobyl radiation induced PTCs in some studies. It usually presents with differential diagnosis of poorly differentiated carcinoma versus anaplastic versus medullary thyroid carcinoma versus metastasis from extrathyroidal malignancy on fine needle aspiration cytology. This report describes a case of solid variant of PTC in a child who had no history of radiation exposure and shows the importance to be given to histopathology when the pre-operative diagnosis is not clear.