Open AccessRestless leg syndrome, periodic limb movements, febrile seizures and Attention deficit hyperactivity disorder in an Indian family
Author(s) -
Meena Gupta,
Amit Batra,
Anurag Trivedi,
Debashish Chowdhury,
Geeta Anjum Khwaja
Publication year - 2012
Publication title -
annals of indian academy of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/0972-2327.93277
Subject(s) - restless legs syndrome , medicine , attention deficit hyperactivity disorder , neurological disorder , affect (linguistics) , family history , incidence (geometry) , pediatrics , neurodevelopmental disorder , psychiatry , physical medicine and rehabilitation , insomnia , psychology , central nervous system disease , physics , communication , optics , autism
Restless leg syndrome (RLS) is a common neurological disorder which can affect individuals of all age groups and incidence increasing with age. It can cause severe sleep disruption and negatively impact quality of life of an individual. Its diagnosis is clinical, based on essential criteria of International RLS Study Group. It can be idiopathic or associated with various medical and other neurological disorders. Idiopathic RLS can be sporadic or may have a familial inheritance, with several genetic loci been reported till date. RLS has a strong association with periodic limb movements, both sleep and awake. Very few studies of familial RLS/Periodic limb movements in sleep and their associations have been reported. We report an Indian family with autosomal dominant RLS/PLMS, with RLS and PLMS as well as psychiatric disorders, febrile seizures and Attention Deficit Hyperactivity Disorder in different family members, over three generations.