Open AccessUse of thrombolytic therapy in cerebral venous sinus thrombosis with ulcerative colitis
Author(s) -
Kavitha Kothur,
Subhash Kaul,
S Rammurthi,
Vishal Bandaru,
Suvarna Alladi T Suryaprabha,
Kandadai Rukmini Mrudula
Publication year - 2012
Publication title -
annals of indian academy of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/0972-2327.93276
Subject(s) - medicine , ulcerative colitis , venous thrombosis , dural venous sinuses , cerebral venous sinus thrombosis , thrombosis , surgery , urokinase , sinus (botany) , disease , botany , biology , genus
Cerebral venous thrombosis developing concurrently with active ulcerative colitis poses a therapeutic dilemma. We report the case of a 31-year-old woman who developed dural venous sinus thrombosis during the course of active ulcerative colitis in whom we accomplished clot lysis using intrasinus urokinase. The success of the procedure was assessed by improvement in the patient's neurological condition and resolution of imaging features without any bleeding complications. We also reviewed literature on various modalities of treatment of sinus venous thrombosis in patients with ulcerative colitis and outcome.