Open AccessPeriodic electroencephalogram discharges in a case of Lafora body disease: An unusual finding
Author(s) -
Rajendra Singh Jain,
Arti Gupta,
Pankaj Gupta,
Rakesh Agrawal
Publication year - 2016
Publication title -
annals of indian academy of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/0972-2327.176862
Subject(s) - myoclonic jerk , medicine , electroencephalography , ataxia , myoclonus , lafora disease , epilepsy , audiology , neuroscience , myoclonic epilepsy , progressive myoclonus epilepsy , psychology , anesthesia , psychiatry , biology , biochemistry , phosphorylation , phosphatase
Lafora body disease (LBD) is a form of progressive myoclonic epilepsy, characterized by seizures, myoclonic jerks, cognitive decline, ataxia, and intracellular polyglucosan inclusion bodies (Lafora bodies) in the neurons, heart, skeletal muscle, liver, and sweat gland duct cells. Electroencephalogram (EEG) findings in LBD may include multiple spikes and wave discharges, photosensitivity, multifocal epileptiform discharges, and progressive slowing in background activity. Periodicity in epileptiform discharges has not been frequently depicted in LBD. We herein report an unusual case of LBD who showed generalized periodic epileptiform discharges in EEG.