Open AccessMuscle histopathology in today′s era of molecular genetics: Role and limitations
Author(s) -
Ishita Pant,
Sujata Chaturvedi,
Kiran Bala,
Suman Kushwaha
Publication year - 2015
Publication title -
annals of indian academy of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/0972-2327.165455
Subject(s) - histopathology , pathology , immunohistochemistry , medicine , h&e stain , biopsy , muscle biopsy , muscle disorder , anatomical pathology
Past few decades have seen an increasing application of techniques like electron microscopy, western blotting, and molecular genetics in the evaluation of muscle diseases. However, due to their limited availability, histopathological interpretation of muscle biopsies still remains an important component of diagnostic approach to muscle diseases. A systematic methodology is required in the evaluation and interpretation of muscle biopsies. This study was undertaken to analyze the histopathological spectrum of 164 muscle biopsies and to assess the diagnostic yield of basic histopathological procedures in the work up of muscle biopsy.