Open AccessIntergenotypic variation of Vitamin B12 and Folate in AD: In north Indian population
Author(s) -
Neelam Chhillar,
Neeraj Singh,
Basu Dev Banerjee,
Kiran Bala,
Mitra Basu,
Deepika Sharma
Publication year - 2014
Publication title -
annals of indian academy of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/0972-2327.138510
Subject(s) - medicine , vitamin b12 , variation (astronomy) , population , physiology , environmental health , astronomy , physics
Changes in lifestyle habits such as diet modification or supplementation have been indicated as probable protective factors for a number of chronic conditions including Alzheimer's disease (AD). With this background, we aim to hypothesize that whether C677T polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene contributes towards the risk of developing AD and its association with vitamin B12 and folate levels.