Open AccessA voxel based comparative analysis using magnetization transfer imaging and T1-weighted magnetic resonance imaging in progressive supranuclear palsy
Author(s) -
Sandhya Mangalore,
Jitender Saini,
Shaik Afsar Pasha,
Ravi Yadav,
Pramod Kumar Pal
Publication year - 2014
Publication title -
annals of indian academy of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/0972-2327.132626
Subject(s) - limbic lobe , medicine , magnetization transfer , magnetic resonance imaging , white matter , progressive supranuclear palsy , voxel , gyrus , voxel based morphometry , limbic system , parahippocampal gyrus , atrophy , temporal lobe , anatomy , pathology , radiology , central nervous system , epilepsy , psychiatry
In progressive supranuclear palsy (PSP) tissue damage occurs in specific cortical and subcortical regions. Voxel based analysis using T1-weighted images depict quantitative gray matter (GM) atrophy changes. Magnetization transfer (MT) imaging depicts qualitative changes in the brain parenchyma. The purpose of our study was to investigate whether MT imaging could indicate abnormalities in PSP.