Open AccessClot composition and treatment approach to acute ischemic stroke: The road so far
Author(s) -
Paramdeep Singh,
Rupinderjeet Kaur,
Amarpreet Kaur
Publication year - 2013
Publication title -
annals of indian academy of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/0972-2327.120433
Subject(s) - medicine , thrombus , magnetic resonance imaging , stroke (engine) , ischemic stroke , radiology , computed tomography , pathophysiology , acute stroke , ischemia , brain ischemia , cardiology , tissue plasminogen activator , mechanical engineering , engineering
Recent histological studies of thrombi retrieved from patients with an acute ischemic stroke using the endovascular thrombectomy devices and correlation with early vessel computed tomography (CT) and magnetic resonance imaging (MRI) characteristics have given relevant insights into the pathophysiology of thrombotic lesions and may facilitate the development of improved reperfusion treatment approaches. We present a review of recent studies on the histopathologic analysis of thrombi, studies of MRI, and CT imaging correlation with thrombus histology, and detailed structural analysis of thromboemboli retrieved by thrombectomy devices during an acute ischemic stroke.