Open AccessChronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener′s granulomatosis
Author(s) -
Latika Gupta,
Anurodh Sharma,
R. K. Sureka,
Sushant Kumar Bhuyan,
Prashant Singh
Publication year - 2013
Publication title -
annals of indian academy of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/0972-2327.116920
Subject(s) - medicine , presentation (obstetrics) , meningitis , vasculitis , differential diagnosis , respiratory tract , dermatology , pathology , disease , rare disease , respiratory system , pediatrics , surgery
Wegener's granulomatosis (WG) is a systemic necrotizing vasculitis that affects the small blood vessels. It mainly affects the upper and lower respiratory tract and kidneys. Central nervous system (CNS) involvement is rare, and has been reported only in about 8% of cases during the course of illness. Initial presentation with neurologic affection, particularly chronic hypertrophic meningitis is very unusual. We report the case of a 34 year old male who presented with chronic hypertrophic meningitis and multiple cranial nerve involvement as the initial manifestation, without respiratory and renal symptoms. This case highlights the difficulties in diagnosing a rare disease with rarer presentation, and at the same time illustrates that Wegener's granulomatosis should be considered in the differential diagnosis of chronic meningitis.