Open AccessVogt-Koyanagi-Harada syndrome presenting with encephalopathy
Author(s) -
Alireza Emami Naeini,
Dana Daneshmand,
Farzin Khorvash,
Ahmad Chitsaz
Publication year - 2013
Publication title -
annals of indian academy of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/0972-2327.112490
Subject(s) - medicine , encephalopathy , vogt–koyanagi–harada disease , disease , pathogenesis , blindness , pediatrics , dermatology , uveitis , pathology , immunology , optometry
VogtKoyanagi-Harada (VKH) is a rare syndrome affecting tissues with melanocytes. The possibility that VKH syndrome has an autoimmune pathogenesis is supported by the high frequency of human leukocyte antigen-DR4 commonly associated with other autoimmune diseases. Eyes are the main affected organ, resulting in blindness. Brain disease as a late onset event is extremely rare. Here, we are reporting a 57-year-old woman with previously diagnosed VKH syndrome, presenting with a late-onset brain encephalopathy. She was treated with corticosteroids and discharged from hospital with good general condition.