Open AccessCaspase 8 gene variants in healthy North Indian population and comparison with worldwide ethnic group variations
Author(s) -
Ginu P. George,
Rama Devi Mittal
Publication year - 2010
Publication title -
indian journal of human genetics
Language(s) - English
Resource type - Journals
eISSN - 0971-6866
pISSN - 1998-362X
DOI - 10.4103/0971-6866.73406
Subject(s) - allele , genotype , genetics , ethnic group , gene , phenotype , allele frequency , disease , caspase , biology , population , polymerase chain reaction , caspase 8 , genotype phenotype distinction , apoptosis , medicine , programmed cell death , environmental health , sociology , anthropology
Many strategies are being used for the quest for the disease causing genes. Inter-individual variations in several genes exist. Thus, even if they share the same disease-associated allele, the genomic backgrounds - and hence potential interacting alleles at other loci - of people with different regional ancestries may differ, with a consequent variation in the severity of their disease.