Open AccessA systematic study on structure and function of ATPase of wuchereria bancrofti
Author(s) -
Md. Saiful Islam,
Noman Ibna Amin Patwary,
Nazmul Hasan Muzahid,
Shah Md. Shahik,
Md Sohel,
Md. Anayet Hasan
Publication year - 2014
Publication title -
toxicology international/indian journal of toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.129
H-Index - 26
eISSN - 0976-5131
pISSN - 0971-6580
DOI - 10.4103/0971-6580.155357
Subject(s) - wuchereria bancrofti , antigenicity , biology , atpase , epitope , homology modeling , biochemistry , lymphatic filariasis , dephosphorylation , protein tertiary structure , enzyme , filariasis , antigen , genetics , helminths , phosphatase , immunology
Analyzing the structures and functions of different proteins of Wuchereria bancrofti is very important because till date no effective drug or vaccine has been discovered to treat lymphatic filariasis (LF). ATPase is one of the most important proteins of Wuchereria bancrofti. Adenosine triphosphate (ATP) converts into adenosine diphosphate (ADP) and a free phosphate ion by the action of these ATPase enzymes. Energy releases from these dephosphorylation reactions drive the other chemical reactions in the cell.