Open Access
Antimutagenic effect of Dioscorea Pentaphylla on genotoxic effect induced by methyl methanesulfonate in the drosophila wing spot test
Author(s) -
G. K. Surya Prakash,
B. B. Hosetti,
BL Dhananjaya
Publication year - 2014
Publication title -
indian journal of toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.129
H-Index - 26
eISSN - 0976-5131
pISSN - 0971-6580
DOI - 10.4103/0971-6580.155341
Subject(s) - ethyl methanesulfonate , methyl methanesulfonate , chemistry , mutagen , drosophila melanogaster , antimutagen , micronucleus test , biochemistry , dna , dna damage , mutation , toxicity , gene , organic chemistry
Plants as dietary sources are known to have several chemoprotective agents. Dioscorea pentaphylla is an important medicinal plant, which is often used as edible food. This study was undertaken to evaluate the antigenotoxic potential of D. pentaphylla extracts on the genotoxic effect induced by methyl methanesulfonate (MMS) in the Drosophila wing spot test.