Open AccessCoenzyme Q10 abrogated the 28 days aluminium chloride induced oxidative changes in rat cerebral cortex
Author(s) -
Anuradha Majumdar,
Abhijit Nirwane,
Rahul Kamble
Publication year - 2014
Publication title -
toxicology international/indian journal of toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.129
H-Index - 26
eISSN - 0976-5131
pISSN - 0971-6580
DOI - 10.4103/0971-6580.139814
Subject(s) - coenzyme q10 , oxidative stress , cerebral cortex , vitamin e , glutathione peroxidase , superoxide dismutase , antioxidant , glutathione , chemistry , endocrinology , lipid peroxidation , catalase , medicine , biochemistry , biology , enzyme
The present study was designed to elucidate the impact of oral administration of aluminium chloride for 28 days with respect to oxidative stress in the cerebral cortex of female rats. Further, to investigate the potentials of Coenzyme (Co) Q10 (4, 8, and 12 mg/kg, i.p.) in mitigating the detrimental changes.