Open AccessIn vivo studies on the protective effect of propolis on doxorubicin-induced toxicity in liver of male rats
Author(s) -
Shivani Singla,
Neelima R. Kumar,
Jaspreet Kaur
Publication year - 2014
Publication title -
toxicology international/indian journal of toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.129
H-Index - 26
eISSN - 0976-5131
pISSN - 0971-6580
DOI - 10.4103/0971-6580.139808
Subject(s) - glutathione , toxicity , pharmacology , glutathione peroxidase , glutathione reductase , malondialdehyde , propolis , chemistry , oxidative stress , transaminase , superoxide dismutase , endocrinology , biochemistry , medicine , enzyme , food science , organic chemistry
Since anticancer drugs are to be administered for long durations of time and are associated with systemic toxicities, the present studies were conducted to evaluate the protective potential of honey bee propolis against a widely used anticancer drug, doxorubicin (DXR) induced toxicity and oxidative damage in liver tissues of rats.