Open AccessLipid metabolism disorders, lymphocytes cells death, and renal toxicity induced by very low levels of deoxynivalenol and fumonisin B1alone or in combination following 7 days oral administration to mice
Author(s) -
Justin Yatty Kouadio,
Serge Moukha,
Kouakou Brou,
D. Gnakri
Publication year - 2013
Publication title -
toxicology international/indian journal of toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.129
H-Index - 26
eISSN - 0976-5131
pISSN - 0971-6580
DOI - 10.4103/0971-6580.121673
Subject(s) - fumonisin b1 , toxicity , kidney , fumonisin , oral administration , pharmacology , chemistry , dna fragmentation , fusarium , apoptosis , in vivo , mycotoxin , metabolism , programmed cell death , medicine , biology , physiology , endocrinology , biochemistry , food science , microbiology and biotechnology , horticulture
In our previous study focused on in vitro interactive effect of Fusarium mycotoxins deoxynivalenol (DON) and fumonisin B1 (FB1), we reported that these toxins tested at low level and in association could lead to additive or synergistic cytotoxic effect. The aim of the present study is to confirm those findings by in vivo study.