Open AccessChemopreventive effect ofBauhinia purpureaagainst chemically induced hepatocarcinogenesis via amelioration of oxidative damage, cell proliferation and induction of apoptosis in Wistar rats
Author(s) -
Safees,
Nemat Ali,
Summya Rashid,
Syed Kazim Hasan,
Sarwat Sultana
Publication year - 2013
Publication title -
toxicology international/indian journal of toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.129
H-Index - 26
eISSN - 0976-5131
pISSN - 0971-6580
DOI - 10.4103/0971-6580.117252
Subject(s) - proliferating cell nuclear antigen , glutathione , glutathione peroxidase , glutathione reductase , antioxidant , catalase , apoptosis , chemistry , pharmacology , oxidative stress , biochemistry , cell growth , microbiology and biotechnology , biology , enzyme
In the present study we have evaluated the chemopreventive efficacy of Bauhinia purpurea against Diethylnitrosamine (DEN) initiated and 2 Acetylaminofluorine (2-AAF) promoted hepatocarcinogenesis in Wistar rats.