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The proposed framework is obtained by casting the noise removal problem into a variational framework. This framework automatically identifies the various types of noise present in the magnetic resonance image and filters them by choosing an appropriate filter. This filter includes two terms: the first term is a data likelihood term and the second term is a prior function. The first term is obtained by minimizing the negative log likelihood of the corresponding probability density functions: Gaussian or Rayleigh or Rician. Further, due to the ill-posedness of the likelihood term, a prior function is needed. This paper examines three partial differential equation based priors which include total variation based prior, anisotropic diffusion based prior, and a complex diffusion (CD) based prior. A regularization parameter is used to balance the trade-off between data fidelity term and prior. The finite difference scheme is used for discretization of the proposed method. The performance analysis and comparative study of the proposed method with other standard methods is presented for brain web dataset at varying noise levels in terms of peak signal-to-noise ratio, mean square error, structure similarity index map, and correlation parameter. From the simulation results, it is observed that the proposed framework with CD based prior is performing better in comparison to other priors in consideration.

journal of medical physics

A partial differential equation-based general framework adapted to Rayleigh's, Rician's and Gaussian's distributed noise for restoration and enhancement of magnetic resonance image