Open AccessPatient dose analysis in total body irradiation through in vivo dosimetry
Author(s) -
K Ganapathy,
P G G Kurup,
V Murali,
M. Muthukumaran,
N Bhuvaneshwari,
J Velmurugan
Publication year - 2012
Publication title -
journal of medical physics/journal of medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.292
H-Index - 24
eISSN - 1998-3913
pISSN - 0971-6203
DOI - 10.4103/0971-6203.103607
Subject(s) - dosimetry , medicine , thermoluminescent dosimeter , nuclear medicine , total body irradiation , in vivo , radiation therapy , lithium fluoride , radiology , surgery , chemotherapy , dosimeter , chemistry , biology , cyclophosphamide , inorganic chemistry , microbiology and biotechnology
Total body irradiation (TBI) is a special radiotherapy technique, administered prior to bone marrow transplantation. Due to the complex nature of the treatment setup, in vivo dosimetry for TBI is mandatory to ensure proper delivery of the intended radiation dose throughout the body. Lithium fluoride (LiF) TLD-100 chips are used for the TBI in vivo dosimetry. Results obtained from the in vivo dosimetry of 20 patients are analyzed. Results obtained from forehead, abdomen, pelvis, and mediastinum showed a similar pattern with the average measured dose from 96 to 97% of the prescription dose. Extremities and chest received a dose greater than the prescription dose in many instances (more than 20% of measurements). Homogeneous dose delivery to the whole body is checked by calculating the mean dose with standard deviation for each fraction. Reasons for the difference between prescription dose and measured dose for each site are discussed. Dose homogeneity within ±10% is achieved using our in-house TBI protocol.