Open AccessPotential diagnostic implications of miR-144 overexpression in human oesophageal cancer
Author(s) -
Priyanka Sharma,
Anoop Saraya,
Rinu Sharma
Publication year - 2016
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/0971-5916.191796
Subject(s) - downregulation and upregulation , cancer , clinical significance , medicine , pathology , real time polymerase chain reaction , gene ontology , gastroenterology , microrna , biology , cancer research , oncology , gene expression , gene , genetics
Insidious symptomatology, late clinical presentation and poor prognosis of oesophageal cancer (EC) highlight the pressing need for novel non-invasive biomarkers for early tumour diagnosis and better prognosis. The present study was carried out to evaluate the clinical significance of circulating and tissue miR-144 expression in oesophageal cancer.